Extremely low Sensitivity of Coronary Risk Equations
Lies, damned lies about the cost-efficiency of statins ….(reference)
Atherosclerosis Progression, LDL and Statins
Statins in Primary Prevention – the discussion is finally over
The Cholesterol Treatment Trialist performed a metaanalysis on 134’537 patients and were able to calculate risk reduction with statins for all risk strata in primary care. Their findings are remarkable. More…
IMT is not suited for tracking cardiovascular risk.
A metaanalysis published on Lancet 2012 has included 36’985 participants and found that IMT changes can not predict future cardiovascular risk. More…
Lipid lowering reduces intracranial stenosis
This is the first prospective multicenter study to demonstrate that high-density lipoprotein cholesterol elevation, along with remnant lipoprotein cholesterol reduction and low apolipoprotein B/A-I, is associated with prevention of angiographic progression of symptomatic intracranial atherosclerotic stenosis. More…
Longterm TPA Follow Up Study (15 years)
A longterm TPA follow-up study from the Tromso cohort revealed that in subjects without plaque annual risk is 7/1000, which is about the risk to experience a myocardial infarction using nuclear scans (refer to TPALongtermTromso2014.pdf). IMT further reduced risk to 4/1000 per year, if IMT was found to be below 0.71 mm. Therefore, in subjects without plaque, IMT offers a small further risk stratificitaion from low risk to very low risk.